The bus, which was carrying 23 Seton Hill lacrosse players and three coaches, reportedly went off the road and crashed into a tree, according to Pennsylvania Turnpike spokeswoman Renee Colborn. The crash occurred around 9 a.m.
Colborn said that the bus driver and one passenger died and 14 passengers were hospitalized, some with serious injuries. Three were taken to the hospital in helicopters, according to Penn State Hershey Medical Center spokeswoman Danielle Ran. One of the three died at the hospital.
Photos from the scene show the bus upright on the side of the road, part of its left side shorn off, though it's not clear whether that was from impact or emergency workers attempting to reach people inside the bus. At least one person was wheeled away in a stretcher.
State police were investigating the crash, said Megan Silverstram of the Cumberland County public safety department, and state environmental officials were also sent to the scene because of a diesel fuel spill from the bus.
The bus operator, Mlaker Charter & Tours, of Davidsville, Pa., sent investigators to the scene, company dispatcher Kelly Hay said. The company had no information yet from the investigators and could not comment, she said.
Seton Hill University is a Catholic school of about 2,500 students, located near Pittsburgh. The team was to play at Millersville University, outside Lancaster, Pa., on Saturday